PRINCIPAL INVESTIGATOR

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Petros C. Karakousis, M.D.

Professor of Medicine

Dr. Petros Karakousis is a Professor of Medicine at the Johns Hopkins University School of Medicine. He has a joint appointment in International Health at the Johns Hopkins Bloomberg School of Public Health. 

 

He graduated summa cum laude from the Johns Hopkins University in 1994 and received a Distinguished Alumni Scholarship to study at the Washington University School of Medicine in St. Louis, where he was inducted into the Alpha Omega Alpha Honor Society in 1998. He completed residency training in Internal Medicine in 2001 at the Hospital of the University of Pennsylvania. After completing fellowship training in Infectious Diseases at Johns Hopkins University School of Medicine, he joined the Department of Medicine faculty in 2005.

CO-INVESTIGATOR

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Research Associate

Noton K. Dutta, Ph.D.

I obtained my Ph.D. from Jadavpur University, India, and did postdoctoral research at Seoul National University, South Korea and Tulane University, USA. I am presently working on multiple projects, including a systems biology-based characterization of animal models of latent TB infection and reactivation, and testing the efficacy of novel drugs and drug combinations in murine and guinea pig TB models.

Hobbies: Traveling, reading, and cooking.

LAB MANAGER

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Pranita Neupane, MD

Research Technologist

I am an ECFMG-certified medical graduate (2014) from Nepal. I have worked as a medical officer in various hospitals in Nepal. I am associated with the USA-based nonprofit organization, "Project for a village" and have volunteered as a health care provider in rural areas of Nepal. 

In order to pursue my research interests, I worked at the National Institute of Health (NIH) on projects related to the pathogenesis of sepsis and septic shock, with special emphasis on Bacillus anthracis. I have also worked as a research volunteer at Johns Hopkins during summer and fall 2019 on studies directed to understanding the underlying mechanism during oxidative stress and atherosclerosis in order to reverse or reduce these effects and changes.

 

In my free time I like to play badminton, gardening, and traditional art like Rangoli and Heena. 

POST-DOCTORAL RESEARCHERS

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Samuel Ayeh, MD, MPH

Post-Doctoral Fellow

I obtained my medical degree from the University of Ghana Medical School in February 2012. After two years of internship, I served for 3 years as a general practitioner. In May 2019, I obtained a Masters in Public Health from The Johns Hopkins Bloomberg School of Public Health with a major in Epidemiology and Biostatistical Methods for Public Health and Clinical Research.


Research Interest: Molecular mechanisms underlying chronic infectious diseases (particularly TB and HIV), and drug development for TB/HIV.


Hobbies: Soccer, Table tennis.

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Vignesh Chidambaram, M.B.B.S., MD

Post-Doctoral Fellow

I received my medical degree from the Jawaharlal Institute of Post-Graduate Medical Education and Research (JIPMER), Pondicherry, India in 2014. I completed my residency in Internal Medicine at the same hospital in 2018. I am currently pursuing my MPH at the Johns Hopkins Bloomberg School of Public Health with a major in Infectious Diseases Epidemiology. 

Research Interest: Epidemiological methods and Modeling in tuberculosis diagnosis and treatment  

 

Hobbies: Playing cricket and playing drums 

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Styliani Karanika, MD

 Infectious Diseases Fellowship

 

I obtained my medical degree from the University of Athens, Medical School in July 2011. I served as a rural physician and resident in Greece until August 2013 when I joined MD Anderson Cancer Center at the University of Texas as a post-doctoral research fellow. There, I worked on projects focused mainly on DNA damage response, activation of immune signaling and mechanisms of apoptosis in in-vitro and in-vivo models. Then, I moved to Brown University in March 2015 where I ran epidemiologic studies in C. difficile, MRSA, ESBL gram negative bacteria.  I was also involved in clinical trials investigating novel diagnostic nanotechnology-based molecular assays for the diagnosis of bacteremia and candidemia. Subsequently, I completed my Internal Medicine residency training at Boston University Medical Center in June 2019 and then I joined fellowship training in Infectious Diseases at Johns Hopkins University School of Medicine. 

Research interest: TB vaccine, HIV, SARS-CoV-2, immunology

Hobbies: Piano, Traveling, Cooking

PRE-DOCTORAL RESEARCHERS

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Monika Looney, B.S.

I received my Bachelor of Science degrees in Microbiology and Psychology from the University of Maryland, College Park in 2016. I am currently a PhD candidate in the Pathobiology program at the Johns Hopkins School of Medicine, conducting my thesis work in the Karakousis Lab. My research focuses on furthering our understanding of host responses to infection withMycobacterium tuberculosis. Current projects are aimed at defining the functional roles of microRNAs, tRNA-derived fragments, and the inflammasome in tuberculosis pathogenesis and treatment using both unbiased, high-throughput and targeted, mechanistic approaches. The ultimate goal of this work is to identify novel targets for host-directed therapy development. 

Current project: Investigating the role of microRNAs in tuberculosis pathogenesis and treatment.

Hobbies: Painting, Mountain Biking, Traveling, Volunteering

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Harley Parker, B.S.

I received my Bachelor of Science degree in Biochemistry from Youngstown State University in 2018. I am now pursuing a Ph.D. in the Pathobiology program at Johns Hopkins School of Medicine and will be conducting my thesis work in the Karakousis lab. My current research focuses on identifying potential drug-targetable genes in Mycobacterium tuberculosis to improve treatment times.

 

Hobbies: Baking, Reading, and Skiing

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Carina Danchik, B.S.

I received my Bachelor of Science in Biology from Franciscan University of Steubenville in 2017. After that, I spent a year and a half as a post-baccalaureate research fellow at the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH). I am now a PhD student in the Cellular and Molecular Medicine program at Johns Hopkins School of Medicine. My current project is focused on testing genes involved in antibiotic tolerance in Mycobacterium avium and Mycobacterium tuberculosis to identify new targets for drug discovery.

 

Hobbies: Baking, Reading, Gardening

UNDERGRADUATE STUDENTS

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Sarah Kohl

B.S. Student in Molecular and Cellular Biology

I am a senior at Johns Hopkins. I am currently studying molecular and cellular biology and public health. My academic interests include infectious diseases and epidemics, particularly tuberculosis, both on a molecular and cellular level and a population level. I am also interested in the challenges to providing health care to rural areas and to populations who typically do not have access. My other interests include cooking, skiing, and traveling. I am also involved with the club softball team and am an EMT.

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Olivia Wang

B.S. Student in Molecular and Cellular Biology

I am a sophomore at Johns Hopkins University studying Molecular and Cellular Biology and Computational Medicine. I am interested in understanding the pathogenesis of tuberculosis infection and the mechanisms by which our immune system defends against it. I am also interested in learning about host-directed therapies for TB. My other hobbies include cooking, grocery shopping, journaling, and travelling.

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Lucas Zhou

B.S. Student in Biomedical Engineering

I am a freshman at Johns Hopkins University studying biomedical engineering (BME). I am interested in exploring the intersection between infectious disease, neuroscience, and BME, especially the application of novel BME methods to clinical treatment.  

My other interests include playing piano and cello, working out at the gym, and traveling. 

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Marissa McDonald

B.S. Student in Biomedical Engineering

I am a sophomore at Johns Hopkins University, studying Biomedical Engineering with a focus in Immunoengineering and a minor in Computational Medicine. I am interested in understanding the dormancy of tuberculosis and using this information to develop more effective antibiotics. I am passionate about engineering for low resource settings, where advancements in science and medicine often do not translate. Outside of the lab, I am the Director of Style for Marque Magazine, Maryland's first and only student-run fashion magazine. I am also on ¡Baila!, JHU's only Latin dance team, and the Worship Coordinator for InterVarsity, one of the Christian fellowships on campus. 

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Alyssa Zimmerman

B.S. Student in Molecular and Cellular Biology

I am a freshman at Johns Hopkins University studying molecular and cellular biology along with environmental science. I am interested in understanding the functions related to dormancy of tuberculosis and exploring antibiotic treatments that may reduce the dormancy period. Aside from academics, I am involved in a few environmental groups on campus and enjoy working out and cooking.

SCIENTIFIC STAFF

Linda Brady

Geltrouda Demczuk

© 2019 - All Rights Reserved - Karakousis Lab

P.C. Monika Looney & Anna Saorin - Inquiries welcome